In a point mutation, a single letter of the genetic code changes to another letter. When a protein gets made from that new code, it'll be different from usual. But new research finds that it may be fairly common for mutations to happen in DNA simultaneously. Which could make big jumps , without waiting for the changes to accrue over generations. The work is in the journal Current Biology. The researchers did close of the genomes of organisms ranging from yeast to fruit flies to the plant Arabidopsis to humans. And they concluded that about three percent of all new mutations must be multiples. A likely explanation is that some polymerase enzyme is prone to errors when it's weaving a strand of DNA. Here's why having multiples could be a big deal. The single mutation-at-a-time view would be like hoping you hit the Pick 4 lottery by getting one number a day for four days. Sadly, what you really get is four losing tickets. But multiple mutations could let you hit the Pick 4 all at once. And win the evolutionary lottery.