A new study published in Cell Reports reveals that oral to nanoplastics, or plastic particulates smaller than 500 nanometers, can affect brain function in mice by inducing inflammation in the gut. The researchers found that nanoplastics were more readily taken up by macrophages in the intestines than larger microplastics, and triggered the production of a pro-inflammatory cytokine. This cytokine then affected the brain through the gut-brain axis, resulting in cognitive and memory impairments. The authors hope that their findings will raise of the potential health risks of nanoplastic pollution, which is a growing environmental concern. They estimate that humans consume about 5 grams of plastic per week, to a credit card. The study adds to the growing body of evidence that microplastics and nanoplastics can have effects on various biological systems, including the reproductive, immune, endocrine, and nervous systems. Previous studies have shown that aquatic species and laboratory animals in contact with plastic particulates exhibit neurotoxicity and endocrine .The authors also note that microplastics have been detected in human tissues, highlighting the need for more research on the impact of plastic pollution on human health.